Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties.
نویسندگان
چکیده
A convenient synthesis of indolin-2-ones substituted in the 3 position by an aminomethylene group bearing different amino acid moieties is described. Their antiproliferative activities were evaluated toward a panel of human solid tumor cell lines (PC 3, DLD-1, MCF-7, M4 Beu, A549, PA 1) and healthy cell lines (a murine fibroblast L929 and a human fibroblast primary culture).
منابع مشابه
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عنوان ژورنال:
- European journal of medicinal chemistry
دوره 41 6 شماره
صفحات -
تاریخ انتشار 2006